The opportunity of a lifetime is only available within the lifetime of the opportunity.
Things in the marketplace are always moving and shifting. This makes it very hard to pick when to zig and when to zag regarding taking advantage of opportunities when you believe they have presented themselves.
The marketplace is cluttered with ideas whose time came and went. Some were capitalized upon and some were missed. Some windows were hit and some were missed.
If waiting means it will be impossible for you to seize an opportunity, perhaps you should take a risk and push ahead. Perhaps you should ask your advisors. Perhaps you should research and gather data.
Doing nothing will guarantee missing the window of opportunity.
Do not regret looking at the broken glass of windows of opportunities that were shattered because you acted after they were closed.